Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.67 |
| ▸ | ACE | P12821 | 12/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334484 | 0.96 | PREP (0.72) | PREPACELMNAALDH1A1CYP3A4 | |
| SCHEMBL22209468 | 0.96 | PREP (0.72) | PREPACELMNAALDH1A1CYP3A4 | |
| SCHEMBL7871516 | 0.96 | PREP (0.72) | PREPACELMNAALDH1A1CYP3A4 | |
| SCHEMBL8611219 | 0.92 | PREP (0.67) | PREPACELMNAALDH1A1CYP3A4 | |
| SCHEMBL8611215 | 0.92 | PREP (0.67) | PREPACELMNAALDH1A1CYP3A4 | |
| SCHEMBL9438697 | 0.92 | PREP (0.67) | PREPACELMNAALDH1A1CYP3A4 | |
| SCHEMBL9438980 | 0.92 | PREP (0.67) | PREPACELMNAALDH1A1CYP3A4 | |
| SCHEMBL9438701 | 0.92 | PREP (0.67) | PREPACELMNAALDH1A1CYP3A4 | |
| SCHEMBL16000756 | 0.89 | PREP (0.71) | PREPACELMNAALDH1A1CYP3A4 | |
| SCHEMBL22209424 | 0.88 | PREP (0.70) | PREPACELMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719200-A | Amino acid derivatives and antihypertensive drugs containing the same | AJINOMOTO CO., INC. (JP) | 1988-01-12 | — | — | US | disclosed |
| EP-0173510-A2 | Tripeptide derivatives for use as anti-hypertensive agents | AJINOMOTO CO., INC. (JP) | 1986-03-05 | — | — | EP | disclosed |