Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.67 |
| ▸ | ACE | P12821 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9438980 | 1.00 | PREP (0.67) | PREPACELMNAFKBP1ASMN1; SMN2 | |
| SCHEMBL9438701 | 1.00 | PREP (0.67) | PREPACELMNAFKBP1ASMN1; SMN2 | |
| SCHEMBL7334484 | 0.96 | PREP (0.72) | PREPACELMNASMN1; SMN2ACE2 | |
| SCHEMBL22209468 | 0.96 | PREP (0.72) | PREPACELMNASMN1; SMN2ACE2 | |
| SCHEMBL7871516 | 0.96 | PREP (0.72) | PREPACELMNASMN1; SMN2ACE2 | |
| SCHEMBL10657907 | 0.92 | PREP (0.67) | PREPACELMNASMN1; SMN2ACE2 | |
| SCHEMBL8611215 | 0.92 | PREP (0.67) | PREPACELMNASMN1; SMN2ACE2 | |
| SCHEMBL8611219 | 0.92 | PREP (0.67) | PREPACELMNASMN1; SMN2ACE2 | |
| SCHEMBL12525696 | 0.91 | PREP (0.66) | PREPACELMNAFKBP1AELANE | |
| SCHEMBL18620614 | 0.91 | PREP (0.66) | PREPACELMNAFKBP1AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348944-A | Hypotensive agents | SCHERING CORPORATION (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0050800-B1 | CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1986-06-18 | — | — | EP | disclosed |
| EP-0050800-A1 | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1982-05-05 | — | — | EP | disclosed |