Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24100736 | 0.91 | LMNA (0.67) | LMNACYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL26120613 | 0.91 | LMNA (0.67) | LMNACYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL10657196 | 0.91 | LMNA (0.48) | LMNACYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL10653360 | 0.91 | LMNA (0.48) | LMNACYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL11281437 | 0.90 | LMNA (0.47) | LMNACYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL10655585 | 0.89 | FNTA (0.49) | LMNACYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL10653336 | 0.89 | FNTA (0.49) | LMNACYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL10653540 | 0.88 | LMNA (0.47) | LMNACYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL6838403 | 0.88 | LMNA (0.47) | LMNACYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL10654417 | 0.88 | LMNA (0.47) | LMNACYP3A4ALDH1A1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4740501-A | ANTITUMOR AGENT | PROTER S.P.A. (IT) | 1988-04-26 | — | — | US | disclosed |
| US-4540683-A | In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound | PROTER S.P.A. (IT) | 1985-09-10 | — | — | US | disclosed |