SCHEMBL10658034

SCHEMBL10658034

C=C(CC(=O)OC(C)(C)CC)C(=O)OC(C)(C)CC

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1067033 0.83
SCHEMBL13554281 0.82
SCHEMBL1067035 0.81 TSHR (0.34) TSHR
SCHEMBL620517 0.81 GAA (0.42) ALDH1A1TSHRTDP1
SCHEMBL8640588 0.80 MMP8 (0.33) TSHR
SCHEMBL30997363 0.80 ALDH1A1 (0.32) ALDH1A1TSHRTDP1
SCHEMBL21439784 0.80 ALDH1A1 (0.32) ALDH1A1TSHRTDP1
SCHEMBL30756683 0.78 ALDH1A1 (0.31) ALDH1A1TSHRTDP1
SCHEMBL8644100 0.78
SCHEMBL678671 0.78 CYP2D6 (0.39) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4743667-A ACRYLATED SILOXXANES, OXYGEN PERMEABLE NIPPON CONTACT LENS, INC. (JP) 1988-05-10 US disclosed