SCHEMBL10658053

SCHEMBL10658053

CC(C)CCCC(C)C=CN1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10658051 1.00 LMNA (0.32) LMNAL3MBTL1
SCHEMBL10658052 1.00 LMNA (0.32) LMNAL3MBTL1
SCHEMBL688561 0.72
SCHEMBL10149589 0.71 NPC1 (0.32) LMNA
SCHEMBL28351367 0.71 NPC1 (0.32) LMNA
SCHEMBL219982 0.68
SCHEMBL219983 0.68
SCHEMBL9113416 0.67
SCHEMBL9113419 0.67
SCHEMBL8967566 0.67 ELANE (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257048-A1 OPTICALLY ACTIVE COMPOUNDS. MERCK PATENT GMBH (DE) 1988-03-02 EP disclosed
WO-1987005018-A2 OPTICALLY ACTIVE COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1987-08-27 WO disclosed