Acrylamide

Acrylamide

SCHEMBL10658901

C=CC(=O)N1CCCCC1.C=CC(N)=O

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
TSHR P16473 1/20 0.48
FGFR4 P22455 1/20 0.48
F2 P00734 1/20 0.39
HSD11B1 P28845 1/20 0.38
KMT2A Q03164 2/20 0.38
TET3 O43151 1/20 0.38
FBXL19 Q6PCT2 1/20 0.38
CXXC5 Q7LFL8 1/20 0.38
TET1 Q8NFU7 1/20 0.38
KDM2B Q8NHM5 1/20 0.38
CXXC4 Q9H2H0 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
TGM2 P21980 1/20 0.36
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
MMP9 P14780 1/20 0.35
HPGD P15428 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10660748 0.91 ALDH1A1 (0.55) ALDH1A1KMT2ATET3FBXL19CXXC5
SCHEMBL2558338 0.91 ALDH1A1 (0.55) ALDH1A1KMT2ATET3FBXL19CXXC5
SCHEMBL2554891 0.91 ALDH1A1 (0.55) ALDH1A1KMT2ATET3FBXL19CXXC5
SCHEMBL10661213 0.91 ALDH1A1 (0.55) ALDH1A1KMT2ATET3FBXL19CXXC5
SCHEMBL10658257 0.91 ALDH1A1 (0.55) ALDH1A1KMT2ATET3FBXL19CXXC5
SCHEMBL25231611 0.91 ALDH1A1 (0.55) ALDH1A1KMT2ATET3FBXL19CXXC5
SCHEMBL329111 0.91 ALDH1A1 (0.55) ALDH1A1KMT2ATET3FBXL19CXXC5
SCHEMBL37699 0.91 ALDH1A1 (0.55) ALDH1A1KMT2ATET3FBXL19CXXC5
SCHEMBL20664588 0.91 ALDH1A1 (0.55) ALDH1A1KMT2ATET3FBXL19CXXC5
SCHEMBL25690078 0.91 ALDH1A1 (0.55) ALDH1A1KMT2ATET3FBXL19CXXC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160305-A Amide compound containing 4, 5-dihydroisoxazole, salt thereof, preparation method and application 华东理工大学 2022-10-11 CN disclosed
US-4729834-A ACRYLIC AMIDE POLYMERS MITSUI TOATSU CHEMICALS, INC. (JP) 1988-03-08 US disclosed