Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 6/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549127 | 0.80 | TSHR (0.50) | TSHRALDH1A1CYP3A4TDP1ESR1 | |
| SCHEMBL1188477 | 0.79 | TSHR (0.44) | TSHRALDH1A1MTORHPGDALOX15 | |
| SCHEMBL30039195 | 0.79 | TSHR (0.44) | TSHRALDH1A1MTORHPGDALOX15 | |
| SCHEMBL11556772 | 0.78 | TSHR (0.48) | TSHRALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL29682262 | 0.77 | MTOR (0.48) | TSHRALDH1A1MTOR | |
| SCHEMBL624160 | 0.77 | MTOR (0.48) | TSHRALDH1A1MTOR | |
| SCHEMBL2585723 | 0.76 | HPGD (0.40) | TSHRALDH1A1MTORHPGDALOX15 | |
| SCHEMBL19433268 | 0.76 | ALOX15 (0.36) | TSHRALDH1A1MTORHPGDALOX15 | |
| SCHEMBL1538464 | 0.74 | TSHR (0.44) | TSHRCYP3A4TDP1ESR1 | |
| SCHEMBL11855879 | 0.74 | CYP3A4 (0.52) | TSHRALDH1A1ALOX15CYP3A4CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783562-A | Process for the preparation of trichloromethyl-substituted aromatic compounds, and trichloromethyl-substituted aromatic compounds obtained in this process | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-08 | — | — | US | disclosed |
| EP-0061029-B1 | PROCESS FOR THE PREPARATION OF TRICHLOROMETHYL-SUBSTITUTED AROMATIC COMPOUNDS | BAYER AG (DE) | 1986-01-08 | — | — | EP | disclosed |
| EP-0061029-A1 | Process for the preparation of trichloromethyl-substituted aromatic compounds | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |