Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599913 | 0.80 | TSHR (0.44) | TSHRCYP3A4TDP1 | |
| SCHEMBL11602444 | 0.80 | TSHR (0.44) | TSHRALOX15ALOX12CYP3A4TDP1 | |
| SCHEMBL10659106 | 0.78 | TSHR (0.43) | TSHRALOX15ALOX12ALDH1A1CYP3A4 | |
| SCHEMBL10969460 | 0.77 | TSHR (0.41) | TSHR | |
| SCHEMBL10969987 | 0.75 | TSHR (0.40) | TSHR | |
| SCHEMBL10969991 | 0.75 | TSHR (0.40) | TSHR | |
| SCHEMBL10969471 | 0.75 | TSHR (0.40) | TSHR | |
| SCHEMBL10871860 | 0.75 | MAPT (0.45) | TSHR | |
| SCHEMBL7863398 | 0.74 | PTPN5 (0.41) | TSHRALDH1A1 | |
| SCHEMBL1134714 | 0.74 | ALDH1A1 (0.46) | TSHRALOX15ALOX12ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163753-A | FROM AN ALIPHATIC ACID ANHYDRIDE AND A TRICHLOROMETHYL AROMATIC COMPOUND | Diaz Chemical Corporation (US) | 1979-08-07 | — | — | US | disclosed |