Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10659140 | 1.00 | KDM4E (0.56) | KDM4ELMNAITGB3ITGA2BRECQL | |
| SCHEMBL7772288 | 0.86 | HDAC3 (0.51) | LMNAITGB3ITGA2BPIN1HDAC2 | |
| SCHEMBL9831124 | 0.85 | CNR2 (0.55) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL9831119 | 0.85 | CNR2 (0.55) | ITGB3ITGA2BCA12CA1CA2 | |
| SCHEMBL4888092 | 0.84 | KDM4E (0.50) | KDM4ELMNAITGB3ITGA2BRECQL | |
| SCHEMBL29637713 | 0.83 | SMN1; SMN2 (0.57) | LMNAITGB3ITGA2BPIN1HDAC2 | |
| SCHEMBL24533898 | 0.81 | PIN1 (0.59) | ITGB3ITGA2BPIN1HDAC2HDAC8 | |
| SCHEMBL4153095 | 0.81 | ITGB3 (0.65) | ITGB3ITGA2BPIN1HDAC2HDAC8 | |
| SCHEMBL5458748 | 0.81 | ITGB3 (0.65) | ITGB3ITGA2BPIN1HDAC2HDAC8 | |
| SCHEMBL4153101 | 0.81 | ITGB3 (0.65) | ITGB3ITGA2BPIN1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |