SCHEMBL10659232

SCHEMBL10659232

C=CCOC(=O)C(C)Oc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CYP3A4 P08684 1/20 0.49
MAPT P10636 1/20 0.48
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
GAA P10253 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46
CYP2C19 P33261 1/20 0.46
HSD17B10 Q99714 2/20 0.45
TP53 P04637 1/20 0.45
ALOX15 P16050 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
CASP1 P29466 1/20 0.44
TSHR P16473 3/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10357757 0.87 KMT2A (0.44) LMNAL3MBTL1CYP3A4MAPTMTNR1A
SCHEMBL10489918 0.86 KMT2A (0.58) LMNAL3MBTL1MAPTKMT2AALDH1A1
SCHEMBL3830677 0.86 LMNA (0.46) LMNAL3MBTL1CYP3A4MAPTGAA
SCHEMBL10343500 0.84 CYP1A2 (0.50) LMNAL3MBTL1GAACYP1A2CYP2C9
SCHEMBL9839653 0.83 LMNA (0.42) LMNAL3MBTL1CYP3A4MAPTGAA
SCHEMBL10489916 0.82 MAPT (0.47) LMNAL3MBTL1CYP3A4MAPTGAA
SCHEMBL9774726 0.81 CYP3A4 (0.46) LMNACYP3A4MAPTMTNR1AMTNR1B
SCHEMBL9170132 0.80 CYP3A4 (0.45) LMNACYP3A4MAPTMTNR1AMTNR1B
SCHEMBL29034853 0.80 CYP3A4 (0.45) LMNAL3MBTL1CYP3A4MAPTGAA
SCHEMBL8076861 0.80 GAA (0.49) LMNAL3MBTL1MAPTMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104649995-A 6-chlorobenzoxazole oxygen phenoxypropionic acid allyl ester compound and application thereof as weeding agent SINOCHEM CORP 2015-05-27 CN claimed
CN-106831631-B A kind of 6- chloro benzo dislikes (thiophene) azoles oxygroup phenoxy propionic acid ester type compound and its application 沈阳中化农药化工研发有限公司 2019-03-12 CN disclosed
CN-104649995-B A kind of 6 chloro benzo oxazole epoxide phenoxy propionic acid allyl ester type compound and its application as herbicide 沈阳中化农药化工研发有限公司 2017-06-09 CN disclosed
CN-104649995-A 6-chlorobenzoxazole oxygen phenoxypropionic acid allyl ester compound and application thereof as weeding agent SINOCHEM CORP 2015-05-27 CN disclosed
US-4767880-A WITH ALKALI METAL ALCOHOLATE, PHENOLATE, HYDROXYPHENOXYPROPIONATE OR HYDROQUINONE SALT HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-30 US disclosed
US-4042711-A Derivatives of biphenyloxy-lower alkanoic acids, salts thereof and their use as antihyperlipidemics BOEHRINGER INGELHEIM GMBH (DT) 1977-08-16 US disclosed
US-4010279-A BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE BOEHRINGER INGELHEIM GMBH (DT) 1977-03-01 US disclosed