Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830677 | 0.85 | LMNA (0.46) | LMNAL3MBTL1POLBKMT2AMAPT | |
| SCHEMBL10343500 | 0.84 | CYP1A2 (0.50) | LMNAL3MBTL1POLBKMT2AMEN1 | |
| SCHEMBL10659232 | 0.83 | LMNA (0.50) | LMNAL3MBTL1POLBKMT2AMAPT | |
| SCHEMBL10489918 | 0.82 | KMT2A (0.58) | LMNAL3MBTL1POLBKMT2AMAPT | |
| SCHEMBL5789487 | 0.81 | LMNA (0.58) | LMNAELANEL3MBTL1POLBKMT2A | |
| SCHEMBL5789486 | 0.81 | LMNA (0.58) | LMNAELANEL3MBTL1POLBKMT2A | |
| SCHEMBL10598197 | 0.81 | CA12 (0.43) | LMNAL3MBTL1KMT2AMAPTKDM4E | |
| SCHEMBL10489916 | 0.81 | MAPT (0.47) | LMNAL3MBTL1KMT2AMAPTPKM | |
| SCHEMBL9839367 | 0.78 | MAPT (0.50) | LMNAELANEL3MBTL1POLBKMT2A | |
| SCHEMBL9837990 | 0.78 | ALDH1A1 (0.46) | LMNAELANEL3MBTL1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008439-A | Synthesis of 2-(4-hydroxyphenoxy) alkanoic acid esters | HOECHST CELANESE CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0334596-A2 | Synthesis of 2-(4-hydroxyphenoxy)alkanoic acid esters | HOECHST CELANESE CORPORATION (US) | 1989-09-27 | — | — | EP | disclosed |