Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814474 | 0.96 | ACE (0.67) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL10655628 | 0.89 | ACE (0.59) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL26616380 | 0.89 | ACE (0.64) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL31376307 | 0.89 | ACE (0.64) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL26616455 | 0.89 | ACE (0.64) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL26616386 | 0.89 | ACE (0.64) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL26616457 | 0.89 | ACE (0.64) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL26616515 | 0.87 | ACE (0.59) | ACELMNASMN1; SMN2 | |
| SCHEMBL26616508 | 0.87 | ACE (0.59) | ACELMNASMN1; SMN2 | |
| SCHEMBL26616548 | 0.86 | ACE (0.60) | ACELMNASMN1; SMN2LTA4HACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719200-A | Amino acid derivatives and antihypertensive drugs containing the same | AJINOMOTO CO., INC. (JP) | 1988-01-12 | — | — | US | disclosed |
| EP-0173510-A2 | Tripeptide derivatives for use as anti-hypertensive agents | AJINOMOTO CO., INC. (JP) | 1986-03-05 | — | — | EP | disclosed |