Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10659600 | 0.96 | ACE (0.62) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL26616455 | 0.93 | ACE (0.64) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL26616380 | 0.93 | ACE (0.64) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL26616386 | 0.93 | ACE (0.64) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL31376307 | 0.93 | ACE (0.64) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL26616457 | 0.93 | ACE (0.64) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL26616515 | 0.91 | ACE (0.59) | ACELMNASMN1; SMN2 | |
| SCHEMBL26616508 | 0.91 | ACE (0.59) | ACELMNASMN1; SMN2 | |
| SCHEMBL26616554 | 0.90 | ACE (0.60) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL26616548 | 0.90 | ACE (0.60) | ACELMNASMN1; SMN2LTA4HACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201741-B1 | DIPEPTIDE DERIVATIVES, PROCESSES FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | SUNTORY LIMITED (JP) | 1991-07-31 | — | — | EP | disclosed |