Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26616455 | 1.00 | ACE (0.64) | ACELMNASMN1; SMN2ACE2LTA4H | |
| SCHEMBL26616380 | 1.00 | ACE (0.64) | ACELMNASMN1; SMN2ACE2LTA4H | |
| SCHEMBL26616457 | 1.00 | ACE (0.64) | ACELMNASMN1; SMN2ACE2LTA4H | |
| SCHEMBL26616386 | 1.00 | ACE (0.64) | ACELMNASMN1; SMN2ACE2LTA4H | |
| SCHEMBL26616548 | 0.97 | ACE (0.60) | ACELMNASMN1; SMN2ACE2LTA4H | |
| SCHEMBL26616554 | 0.97 | ACE (0.60) | ACELMNASMN1; SMN2ACE2LTA4H | |
| SCHEMBL9814474 | 0.93 | ACE (0.67) | ACELMNASMN1; SMN2ACE2LTA4H | |
| SCHEMBL31376312 | 0.92 | ACE (0.57) | ACELMNASMN1; SMN2 | |
| SCHEMBL30674426 | 0.92 | ACE (0.57) | ACELMNASMN1; SMN2 | |
| SCHEMBL26616536 | 0.92 | ACE (0.57) | ACELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451944-A | PREP binding ligands | 珀尔库治疗有限公司 | 2025-02-14 | — | — | CN | disclosed |