Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10660651 | 0.92 | MAOB (0.50) | MAOBNPC1MAOAPKML3MBTL1 | |
| SCHEMBL10659949 | 0.86 | MAOB (0.52) | MAOBNPC1MAOAPKML3MBTL1 | |
| SCHEMBL10659155 | 0.80 | MAOB (0.49) | MAOBNPC1MAOAPKML3MBTL1 | |
| SCHEMBL4516193 | 0.77 | MAOB (0.58) | MAOBNPC1MAOAPKML3MBTL1 | |
| SCHEMBL10657318 | 0.74 | MAOB (0.52) | MAOBNPC1MAOAPKML3MBTL1 | |
| SCHEMBL11239313 | 0.73 | MAOB (0.45) | MAOBL3MBTL1TDP1MEN1MTNR1A | |
| SCHEMBL10661111 | 0.73 | ABCB1 (0.61) | MAOBNPC1MAOAPKML3MBTL1 | |
| Dihydro-5,6-Dehydrokawain SCHEMBL19679894 | 0.73 | PPARG (0.59) | NPC1L3MBTL1RAB9ATDP1MEN1 | |
| SCHEMBL4568936 | 0.72 | CYP4F2 (0.66) | MAOBBCHE | |
| SCHEMBL27312245 | 0.71 | LTA4H (0.70) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |