Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL8679327 | 0.85 | IDH1 (0.47) | MAOBNPC1MAOAPKMRAB9A | |
| SCHEMBL10659949 | 0.81 | MAOB (0.52) | MAOBNPC1MAOAPKMRAB9A | |
| SCHEMBL10657318 | 0.81 | MAOB (0.52) | MAOBNPC1MAOAPKMRAB9A | |
| SCHEMBL10661111 | 0.79 | ABCB1 (0.61) | MAOBNPC1MAOAPKMRAB9A | |
| SCHEMBL10660651 | 0.79 | MAOB (0.50) | MAOBNPC1MAOAPKMRAB9A | |
| SCHEMBL10659155 | 0.78 | MAOB (0.49) | MAOBNPC1MAOAPKMRAB9A | |
| SCHEMBL7964491 | 0.77 | KDM4E (0.60) | NPC1PKMRAB9AMEN1KMT2A | |
| SCHEMBL10659602 | 0.77 | MAOB (0.48) | MAOBNPC1MAOAPKMRAB9A | |
| SCHEMBL25173859 | 0.76 | ACHE (0.54) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL6173807 | 0.75 | MAOA (0.50) | MAOBNPC1MAOARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731344-A | DIABETES, ATHEROSCLEROSIS, ARTERIOSCLEROSIS; INHIBITORS OF ADVANCED GLYCOSYLATION ENDPRODUCTS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-03-24 | — | — | US | claimed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-6288109-B1 | Pyranones, method for the production and use thereof | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 2001-09-11 | — | — | US | disclosed |
| EP-1032572-A2 | PYRANONES, METHOD FOR THE PRODUCTION AND USE THEREOF | Dr. Willmar Schwabe GmbH & Co. (DE) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999025716-A9 | PYRANONES, METHOD FOR THE PRODUCTION AND USE THEREOF | SCHWABE WILLMAR GMBH & CO (DE) | 1999-09-02 | — | — | WO | disclosed |
| WO-1999025716-A2 | PYRANONES, METHOD FOR THE PRODUCTION AND USE THEREOF | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1999-05-27 | — | — | WO | disclosed |
| US-4745116-A | INHIBITORS OF SERINE PROTEASE | SYNTEX (U.S.A.) INC. (US) | 1988-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | MAOB 4469/4885NPC1 691/4885MAOA 4558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.