Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 6/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5259133 | 0.84 | GSK3B (0.57) | NPC1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5260478 | 0.81 | MAPT (0.52) | STSL3MBTL1HPGDMAPTALDH1A1 | |
| SCHEMBL10574446 | 0.81 | KMT2A (0.59) | MAPTALDH1A1TP53HTT | |
| SCHEMBL5010216 | 0.79 | SMN1; SMN2 (0.56) | STSHSD17B3L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL30669210 | 0.78 | NQO1 (0.38) | SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9482865 | 0.77 | HPGD (0.57) | L3MBTL1HPGDSMN1; SMN2MAPTHTT | |
| SCHEMBL26254861 | 0.76 | HSD17B3 (0.82) | STSHSD17B3L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL7312018 | 0.76 | KMT2A (0.41) | L3MBTL1HPGDSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL705208 | 0.75 | MAPT (0.68) | STSHSD17B3L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL28750349 | 0.73 | MMP1 (0.65) | STSHSD17B3L3MBTL1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791200-A | ANTISECRETORY AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-12-13 | — | — | US | disclosed |