Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5260478 | 0.80 | MAPT (0.52) | KMT2APARP10ALDH1A1HPGDNPSR1 | |
| SCHEMBL10574446 | 0.80 | KMT2A (0.59) | KMT2AALDH1A1HTTMAPTTP53 | |
| SCHEMBL5747150 | 0.80 | KMT2A (0.63) | KMT2APARP10ALDH1A1CYP1A2MEN1 | |
| SCHEMBL5259133 | 0.79 | GSK3B (0.57) | KMT2APARP10 | |
| SCHEMBL4460034 | 0.78 | KMT2A (0.41) | KMT2APARP10ALDH1A1CYP1A2MEN1 | |
| SCHEMBL30669210 | 0.77 | NQO1 (0.38) | KMT2AALDH1A1SMN1; SMN2ESR1HIF1A | |
| SCHEMBL10799504 | 0.77 | ALOX15 (0.54) | KMT2APARP10ALDH1A1CYP1A2MEN1 | |
| SCHEMBL5743825 | 0.77 | PARP10 (0.58) | KMT2APARP10ALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9482865 | 0.76 | HPGD (0.57) | KMT2ACYP1A2MEN1SMN1; SMN2HPGD | |
| SCHEMBL10659869 | 0.76 | STS (0.53) | ALDH1A1SMN1; SMN2HPGDHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880824-A | CARDIOVASCULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-14 | — | — | US | disclosed |
| US-4791200-A | ANTISECRETORY AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-12-13 | — | — | US | disclosed |