Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | MMP1 | P03956 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 6/20 | 0.58 |
| ▸ | THRA | P10827 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HRH2 | P25021 | 4/20 | 0.56 |
| ▸ | HRH1 | P35367 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753195 | 0.91 | L3MBTL1 (0.77) | L3MBTL1MMP1NPC1THRBTHRA | |
| SCHEMBL7244974 | 0.90 | L3MBTL1 (0.71) | L3MBTL1MMP1NPC1THRBTHRA | |
| SCHEMBL11705672 | 0.90 | L3MBTL1 (0.76) | L3MBTL1MMP1NPC1THRBTHRA | |
| SCHEMBL28384699 | 0.90 | L3MBTL1 (0.71) | L3MBTL1MMP1NPC1THRBTHRA | |
| SCHEMBL11434554 | 0.87 | THRA (0.76) | L3MBTL1MMP1THRBTHRAHRH2 | |
| SCHEMBL6640853 | 0.86 | L3MBTL1 (0.60) | L3MBTL1MMP1NPC1MAPTHRH2 | |
| SCHEMBL1291801 | 0.85 | L3MBTL1 (0.68) | L3MBTL1MMP1NPC1THRBTHRA | |
| SCHEMBL11878390 | 0.83 | L3MBTL1 (0.66) | L3MBTL1MMP1NPC1THRBTHRA | |
| SCHEMBL1373310 | 0.83 | L3MBTL1 (0.57) | L3MBTL1MMP1NPC1THRBTHRA | |
| SCHEMBL14872270 | 0.83 | L3MBTL1 (0.65) | L3MBTL1MMP1NPC1THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791200-A | ANTISECRETORY AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-12-13 | — | — | US | disclosed |