Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552544 | 0.80 | HSP90AA1 (0.41) | ALOX15MAPK1TDP1ALDH1A1HSP90AA1 | |
| SCHEMBL11550638 | 0.78 | TSHR (0.60) | ALOX15MAPK1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL11602444 | 0.78 | TSHR (0.44) | ALOX15MAPK1TDP1TSHRCYP3A4 | |
| SCHEMBL11553868 | 0.78 | TSHR (0.60) | MAPK1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL11602607 | 0.75 | CYP3A4 (0.36) | MAPK1TDP1TSHRCYP3A4 | |
| SCHEMBL12732927 | 0.75 | ALOX15 (0.42) | ALOX15MAPK1TDP1ALDH1A1HSP90AA1 | |
| SCHEMBL672252 | 0.75 | NOTUM (0.47) | ALOX15MAPK1TDP1ALDH1A1HSP90AA1 | |
| SCHEMBL18242050 | 0.73 | HSP90AA1 (0.44) | ALOX15MAPK1TDP1ALDH1A1HSP90AA1 | |
| SCHEMBL10972083 | 0.73 | CYP3A4 (0.34) | MAPK1TDP1TSHRCYP3A4 | |
| SCHEMBL10972079 | 0.73 | TSHR (0.34) | MAPK1TDP1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783562-A | Process for the preparation of trichloromethyl-substituted aromatic compounds, and trichloromethyl-substituted aromatic compounds obtained in this process | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-08 | — | — | US | disclosed |
| EP-0061029-B1 | PROCESS FOR THE PREPARATION OF TRICHLOROMETHYL-SUBSTITUTED AROMATIC COMPOUNDS | BAYER AG (DE) | 1986-01-08 | — | — | EP | disclosed |
| EP-0031436-B1 | A METHOD FOR THE CLEAVAGE OF SILOXANES | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1984-02-15 | — | — | EP | disclosed |
| EP-0061029-A1 | Process for the preparation of trichloromethyl-substituted aromatic compounds | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
| US-4310680-A | METAL OR METAL COMPOUND CATALYST | DYNAMIT NOBEL AG (DE) | 1982-01-12 | — | — | US | disclosed |
| EP-0031436-A2 | A method for the cleavage of siloxanes | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1981-07-08 | — | — | EP | disclosed |
| US-4163753-A | FROM AN ALIPHATIC ACID ANHYDRIDE AND A TRICHLOROMETHYL AROMATIC COMPOUND | Diaz Chemical Corporation (US) | 1979-08-07 | — | — | US | disclosed |