Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662332 | 0.80 | ALOX15 (0.42) | HSP90AA1TLR9ALOX15MAPK1TDP1 | |
| SCHEMBL27413372 | 0.78 | TSHR (0.43) | ALOX15MAPK1TDP1ALDH1A1TSHR | |
| SCHEMBL11599913 | 0.78 | TSHR (0.44) | MAPK1TDP1TSHRCYP3A4MAPT | |
| SCHEMBL8576899 | 0.76 | KDM1A (0.34) | ALOX15MAPK1TDP1TSHRCYP3A4 | |
| SCHEMBL11602607 | 0.75 | CYP3A4 (0.36) | MAPK1TDP1TSHRCYP3A4 | |
| SCHEMBL30645676 | 0.75 | PTGDR2 (0.44) | HSP90AA1TLR9ALOX15MAPK1TDP1 | |
| SCHEMBL31373428 | 0.75 | KDM1A (0.48) | HSP90AA1TLR9ALOX15KDM1AMEN1 | |
| SCHEMBL7178861 | 0.75 | PTGDR2 (0.44) | HSP90AA1TLR9ALOX15MAPK1TDP1 | |
| SCHEMBL31373429 | 0.75 | KDM1A (0.48) | HSP90AA1TLR9ALOX15KDM1AMEN1 | |
| SCHEMBL394303 | 0.75 | KDM1A (0.48) | HSP90AA1TLR9ALOX15KDM1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163753-A | FROM AN ALIPHATIC ACID ANHYDRIDE AND A TRICHLOROMETHYL AROMATIC COMPOUND | Diaz Chemical Corporation (US) | 1979-08-07 | — | — | US | disclosed |