Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 20/20 | 0.78 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.76 |
| ▸ | PLK4 | O00444 | 1/20 | 0.73 |
| ▸ | CDK2 | P24941 | 1/20 | 0.73 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.73 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.73 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.73 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4399634 | 0.98 | ADORA2B (0.78) | ADORA2BADORA2AADORA1ADORA3PLK4 | |
| SCHEMBL1060893 | 0.91 | ADORA2B (0.77) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4406403 | 0.90 | ADORA2B (0.80) | ADORA2BADORA2AADORA1ADORA3PLK4 | |
| SCHEMBL1067171 | 0.88 | ADORA2B (0.78) | ADORA2BADORA2AADORA1ADORA3PLK4 | |
| SCHEMBL1064677 | 0.87 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL242517 | 0.87 | ADORA2B (1.00) | ADORA2BADORA2AADORA1ADORA3PLK4 | |
| SCHEMBL1059556 | 0.86 | ADORA2B (0.78) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1061290 | 0.86 | ADORA2B (0.75) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4404242 | 0.85 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1083460 | 0.85 | ADORA2B (0.78) | ADORA2BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268641-B1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | ADVINUS THERAPEUTICS PVT LTD (IN) | 2014-09-03 | — | — | EP | claimed |
| US-8252797-B2 | Heterocyclic compounds as adenosine receptor antagonist | ADVINUS THERAPEUTICS PVT. LTD. (IN) | 2012-08-28 | — | — | US | claimed |
| EP-2268641-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | Advinus Therapeutics Pvt. Ltd. (IN) | 2011-01-05 | — | — | EP | claimed |
| US-20090298744-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | ADVINUS THERAPEUTICS PVT. LTD. (IN) | 2009-12-03 | — | — | US | claimed |
| WO-2009118759-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | ADVINUS THERAPEUTICS PVT. LTD., (IN) | 2009-10-01 | — | — | WO | claimed |
| EP-2268641-B1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | ADVINUS THERAPEUTICS PVT LTD (IN) | 2014-09-03 | — | — | EP | disclosed |
| US-8252797-B2 | Heterocyclic compounds as adenosine receptor antagonist | ADVINUS THERAPEUTICS PVT. LTD. (IN) | 2012-08-28 | — | — | US | disclosed |
| US-20090298744-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | ADVINUS THERAPEUTICS PVT. LTD. (IN) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298744-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | ADORA2A, ADORA3, ADORA1 | ADORA2B 4/4885ADORA2A 1/4885ADORA1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.