Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23642505 | 0.77 | FFAR1 (0.34) | HDAC1CYP4F2CYP4A11 | |
| SCHEMBL1081487 | 0.76 | ALDH1A1 (0.37) | CYP1A2CYP2D6TDP1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1079273 | 0.75 | ALDH1A1 (0.36) | CYP1A2CYP2D6TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL4664162 | 0.74 | GRM2 (0.40) | KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL29195918 | 0.74 | FFAR1 (0.33) | HDAC1 | |
| SCHEMBL1062839 | 0.72 | LPAR1 (0.35) | HDAC1HDAC7HDAC3HDAC4HDAC2 | |
| SCHEMBL1063246 | 0.72 | LPAR1 (0.35) | HDAC1HDAC7HDAC3HDAC4HDAC2 | |
| SCHEMBL17438091 | 0.71 | SMN1; SMN2 (0.48) | CYP1A2CYP2D6RAB9ASMN1; SMN2 | |
| SCHEMBL17454448 | 0.71 | ALDH1A1 (0.38) | CYP1A2CYP2D6TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL223674 | 0.71 | ALDH1A1 (0.42) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268633-A1 | PYRIDAZINONE GLUCOKINASE ACTIVATORS | F. Hoffmann-La Roche AG (CH) | 2011-01-05 | — | — | EP | disclosed |