Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 18/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062839 | 1.00 | LPAR1 (0.35) | LPAR1HDAC1HDAC7RORCHDAC3 | |
| SCHEMBL1082327 | 0.76 | ADA (0.35) | — | |
| SCHEMBL2701890 | 0.76 | ADA (0.35) | — | |
| Hydrochloric Acid SCHEMBL1082147 | 0.75 | ADA (0.34) | — | |
| SCHEMBL1066313 | 0.72 | HDAC1 (0.39) | HDAC1HDAC7HDAC3HDAC4HDAC2 | |
| SCHEMBL1067071 | 0.72 | ALDH1A1 (0.40) | RORC | |
| SCHEMBL1080403 | 0.72 | ALDH1A1 (0.40) | RORC | |
| SCHEMBL1067067 | 0.72 | ALDH1A1 (0.40) | RORC | |
| SCHEMBL1062843 | 0.71 | EPHX1 (0.33) | — | |
| SCHEMBL1062836 | 0.71 | EPHX1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268633-A1 | PYRIDAZINONE GLUCOKINASE ACTIVATORS | F. Hoffmann-La Roche AG (CH) | 2011-01-05 | — | — | EP | disclosed |