Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10575573 | 0.99 | MAPK1 (0.54) | KCNH2KMT2AMAPK1GAAMAPT | |
| SCHEMBL10571685 | 0.85 | KCNH2 (0.56) | KCNH2KMT2AMAPK1GAAMAPT | |
| SCHEMBL11071393 | 0.85 | SCN1A (0.49) | KCNH2SCN1ASCN5ASCN9A | |
| SCHEMBL10569047 | 0.83 | DRD2 (0.50) | HTR7 | |
| SCHEMBL10572916 | 0.79 | KCNH2 (0.58) | KCNH2KMT2AMAPK1GAAMAPT | |
| SCHEMBL10570913 | 0.78 | KCNH2 (0.62) | KCNH2KMT2AMAPK1MAPTHTR7 | |
| SCHEMBL11476354 | 0.78 | TSHR (0.54) | KCNH2KMT2AMAPK1GAAMAPT | |
| SCHEMBL11486208 | 0.78 | MAPT (0.50) | KCNH2KMT2AMAPK1GAAMAPT | |
| SCHEMBL10571929 | 0.78 | SCN5A (0.68) | KCNH2KMT2AMAPK1GAAMAPT | |
| Hydrochloric Acid SCHEMBL10572468 | 0.77 | KCNH2 (0.61) | KCNH2KMT2AMAPK1MAPTHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |