Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474394 | 0.91 | KCNH2 (0.58) | MAPTKMT2AKCNH2HTR7MAPK1 | |
| SCHEMBL11474264 | 0.90 | SCN1A (0.47) | MAPTKMT2AMEN1TDP1SCN1A | |
| SCHEMBL11490809 | 0.90 | MEN1 (0.55) | MAPTKMT2AMEN1TDP1TP53 | |
| SCHEMBL11476354 | 0.89 | TSHR (0.54) | MAPTKMT2AMEN1TDP1SCN1A | |
| Hydrochloric Acid SCHEMBL11482853 | 0.88 | TSHR (0.53) | MAPTKMT2AMEN1TDP1SCN1A | |
| SCHEMBL11486191 | 0.88 | ABCB1 (0.53) | SCN1ASCN5ASCN9AABCB1KCNH2 | |
| SCHEMBL11474584 | 0.88 | SCN1A (0.49) | MAPTKMT2AMEN1TDP1SCN1A | |
| SCHEMBL11475983 | 0.87 | MEN1 (0.47) | KMT2AMEN1GAAABCB1KCNH2 | |
| Hydrochloric Acid SCHEMBL11079822 | 0.87 | HTR7 (0.51) | MAPTKMT2AMEN1TDP1SCN1A | |
| SCHEMBL11490020 | 0.87 | ABCB1 (0.55) | SCN1ASCN5ASCN9AABCB1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210753-A | TREATMENT OF CARDIAC DISORDERS AND CHRONIC LUNG DISEASE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-07-01 | — | — | US | disclosed |