Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 1.00 |
| ▸ | DRD3 | P35462 | 6/20 | 1.00 |
| ▸ | DRD4 | P21917 | 5/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13532791 | 0.97 | DRD2 (0.94) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL252623 | 0.93 | DRD2 (1.00) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL7929 | 0.88 | DRD2 (0.93) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL253846 | 0.88 | DRD2 (0.90) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL252032 | 0.85 | DRD2 (1.00) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL252086 | 0.85 | DRD2 (0.88) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL2424904 | 0.84 | DRD2 (0.72) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL23097703 | 0.84 | DRD2 (0.72) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL252898 | 0.84 | SLC6A2 (0.74) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL13532797 | 0.84 | DRD2 (0.87) | DRD2DRD3DRD4SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | claimed |