Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.94 |
| ▸ | DRD3 | P35462 | 8/20 | 0.94 |
| ▸ | DRD4 | P21917 | 7/20 | 0.94 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | DRD1 | P21728 | 1/20 | 0.66 |
| ▸ | DRD5 | P21918 | 1/20 | 0.66 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.66 |
| ▸ | HTR1D | P28221 | 1/20 | 0.66 |
| ▸ | HTR1B | P28222 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | HTR1E | P28566 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10664987 | 0.97 | DRD2 (1.00) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL252623 | 0.96 | DRD2 (1.00) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL7929 | 0.91 | DRD2 (0.93) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL252086 | 0.88 | DRD2 (0.88) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL252032 | 0.88 | DRD2 (1.00) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL13532797 | 0.87 | DRD2 (0.87) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL252902 | 0.86 | DRD2 (1.00) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL253846 | 0.85 | DRD2 (0.90) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL253284 | 0.84 | SLC6A2 (0.74) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| SCHEMBL20029449 | 0.84 | DRD2 (0.71) | DRD2DRD3DRD4SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | HTR6, GAP43, HTR5A | DRD2 242/4885DRD3 432/4885DRD4 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.