Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.53 |
| ▸ | PPARG | P37231 | 18/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10661841 | 0.89 | MAPT (0.41) | PPARAPPARG | |
| SCHEMBL10655642 | 0.85 | PPARA (0.36) | PPARAPPARG | |
| SCHEMBL10738125 | 0.83 | PPARG (0.44) | PPARAPPARG | |
| SCHEMBL10655640 | 0.80 | PPARG (0.33) | PPARAPPARG | |
| SCHEMBL4035353 | 0.79 | FFAR4 (0.44) | PPARAPPARG | |
| SCHEMBL10657410 | 0.78 | MAPT (0.41) | PPARAPPARG | |
| SCHEMBL10659373 | 0.78 | KDM4E (0.42) | PPARAPPARG | |
| SCHEMBL10665132 | 0.78 | PPARA (0.40) | PPARAPPARG | |
| SCHEMBL10661218 | 0.77 | MAPT (0.43) | PPARAPPARG | |
| SCHEMBL10657284 | 0.77 | FFAR4 (0.40) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728662-A | DIURETICS, URICOSURICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-03-01 | — | — | US | disclosed |