Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 11/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.45 |
| ▸ | GCGR | P47871 | 10/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | FRK | P42685 | 2/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.45 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666222 | 0.99 | MAPK13 (0.46) | LMNAMAPTMAPK13MAPK12MAPK11 | |
| SCHEMBL10867051 | 0.89 | KDM4E (0.48) | LMNAMAPTMAPK13MAPK12MAPK11 | |
| SCHEMBL10665379 | 0.88 | LMNA (0.57) | LMNAMAPTMAPK13MAPK12MAPK11 | |
| SCHEMBL10668132 | 0.87 | TSHR (0.56) | LMNAMAPTMAPK13MAPK12MAPK11 | |
| SCHEMBL10666381 | 0.82 | NPY5R (0.52) | LMNAMAPTMAPK13MAPK12MAPK11 | |
| SCHEMBL10666227 | 0.81 | NPY5R (0.50) | LMNAMAPTMAPK13MAPK12MAPK11 | |
| SCHEMBL10666766 | 0.80 | NPY5R (0.51) | PRKCINPY5R | |
| SCHEMBL10664793 | 0.79 | ALDH1A1 (0.49) | LMNAMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL10663382 | 0.78 | NPY5R (0.49) | PRKCINPY5R | |
| SCHEMBL10662517 | 0.78 | MAPK11 (0.51) | LMNAMAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728644-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0168500-A1 | PURINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-01-22 | — | — | EP | disclosed |