Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 13/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10398021 | 0.82 | PTAFR (0.51) | PTAFR | |
| SCHEMBL10399383 | 0.68 | PTAFR (0.70) | PTAFRTBXAS1 | |
| SCHEMBL10398980 | 0.68 | PTAFR (0.54) | PTAFR | |
| SCHEMBL10666706 | 0.67 | PTAFR (0.65) | PTAFR | |
| SCHEMBL10397708 | 0.67 | PTAFR (0.51) | PTAFRTBXAS1 | |
| SCHEMBL10673055 | 0.67 | PTAFR (0.70) | PTAFR | |
| SCHEMBL21176344 | 0.66 | ALDH1A1 (0.44) | PTAFRALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7751185 | 0.63 | CHRNA7 (0.77) | TBXAS1 | |
| SCHEMBL8199625 | 0.63 | TDP1 (0.61) | TBXAS1 | |
| SCHEMBL7594151 | 0.63 | TDP1 (0.53) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |