Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10667124 | 1.00 | ACE (0.47) | ACEMMEALDH1A1MEN1CRHBP | |
| SCHEMBL10942540 | 0.86 | PTPN1 (0.50) | ACETDP1LMNAHSD17B10PPARG | |
| SCHEMBL10805856 | 0.86 | PTPN1 (0.50) | ACETDP1LMNAHSD17B10PPARG | |
| SCHEMBL4954825 | 0.85 | FNTA (0.54) | ACEALDH1A1MEN1CRHBPKMT2A | |
| SCHEMBL28330861 | 0.84 | ALDH1A1 (0.47) | ACEALDH1A1MEN1CRHBPKMT2A | |
| SCHEMBL28330860 | 0.84 | ALDH1A1 (0.47) | ACEALDH1A1MEN1CRHBPKMT2A | |
| SCHEMBL1768156 | 0.83 | ACE (0.51) | ACEALDH1A1MEN1CRHBPKMT2A | |
| SCHEMBL2419579 | 0.83 | ACE (0.51) | ACEALDH1A1MEN1CRHBPKMT2A | |
| SCHEMBL6411060 | 0.83 | ACE (0.51) | ACEALDH1A1MEN1CRHBPKMT2A | |
| SCHEMBL4956801 | 0.81 | LMNA (0.49) | ACEALDH1A1MEN1CRHBPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745124-A | THIO/ESTER PEPTIDES | UNIVERSITY OF MIAMI (US) | 1988-05-17 | — | — | US | disclosed |