SCHEMBL10667282

SCHEMBL10667282

[CH2]CCNC(=O)CCCCCl

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.56
SMN1; SMN2 Q16637 2/20 0.42
TSHR P16473 2/20 0.42
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.39
CNR1 P21554 2/20 0.39
CNR2 P34972 2/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
DNM1 Q05193 2/20 0.38
RECQL P46063 1/20 0.36
CASP2 P42575 1/20 0.35
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8939136 0.81 TSHR (0.43) FAAHSMN1; SMN2TSHRALDH1A1MAPT
SCHEMBL21674074 0.80 FAAH (0.61) FAAHSMN1; SMN2TSHRALDH1A1MAPT
SCHEMBL9034972 0.79 FAAH (0.63) FAAHALDH1A1CNR1HPGDDNM1
SCHEMBL8863653 0.79 SLC6A5 (0.50) FAAHSMN1; SMN2TSHRALDH1A1RECQL
SCHEMBL16799424 0.78 SLC6A5 (0.53) FAAHSMN1; SMN2TSHRALDH1A1DNM1
SCHEMBL9469998 0.78 FAAH (0.67) FAAHALDH1A1CNR1CNR2HPGD
SCHEMBL430817 0.78 FAAH (0.67) FAAHALDH1A1CNR1CNR2HPGD
SCHEMBL713149 0.78 FAAH (0.67) FAAHALDH1A1CNR1CNR2HPGD
SCHEMBL5244402 0.78 FAAH (0.67) FAAHALDH1A1CNR1CNR2HPGD
SCHEMBL74736 0.78 FAAH (0.67) FAAHALDH1A1CNR1CNR2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4792628-A ANTIOXIDANTS, ANTIINFLAMMATORY AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-12-20 US disclosed