Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501648 | 1.00 | DRD2 (0.43) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL7490325 | 0.90 | TAAR1 (0.48) | TAAR1 | |
| SCHEMBL28354373 | 0.86 | MAPT (0.49) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL27441724 | 0.84 | KCNH2 (0.43) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL27811355 | 0.81 | MAPT (0.46) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL27906683 | 0.76 | TAAR1 (0.46) | LMNATAAR1 | |
| SCHEMBL2303570 | 0.76 | DRD2 (0.54) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL10501653 | 0.76 | DRD2 (0.58) | DRD2HTR1AHTR2ADRD3TMEM97 | |
| SCHEMBL4460305 | 0.75 | TAAR1 (0.50) | CNR1TAAR1 | |
| SCHEMBL27613782 | 0.75 | IDO1 (0.50) | LMNATAAR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4751240-A | ANTIFERTILITY AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-06-14 | — | — | US | claimed |
| EP-0163416-A2 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-12-04 | — | — | EP | claimed |