Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759868 | 0.83 | GRM2 (0.46) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL10888984 | 0.82 | HPGD (0.55) | TDP1ALDH1A1SLC9A1SMN1; SMN2TP53 | |
| SCHEMBL10662798 | 0.80 | ALDH1A1 (0.44) | LMNATDP1MEN1KMT2AGAA | |
| SCHEMBL4757995 | 0.79 | HSD17B10 (0.42) | LMNAMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11116273 | 0.78 | GAA (0.60) | LMNATDP1MEN1KMT2AGAA | |
| SCHEMBL28047936 | 0.74 | LMNA (0.50) | LMNATDP1MEN1KMT2AGAA | |
| SCHEMBL4790589 | 0.74 | POLB (0.45) | LMNATDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL9478376 | 0.73 | NPC1 (0.56) | LMNATDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL14911740 | 0.72 | LMNA (0.42) | LMNATDP1MEN1KMT2AGAA | |
| SCHEMBL4790828 | 0.71 | MAPT (0.49) | LMNATDP1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789680-A | Aralkyltriazole compounds | CIBA-GEIGY CORPORATION (US) | 1988-12-06 | — | — | US | disclosed |