Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668039 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPTNPC1RAB9AHPGD | |
| SCHEMBL10669461 | 0.78 | KDM4E (0.41) | ALDH1A1MAPTNPC1RAB9AHPGD | |
| SCHEMBL10669455 | 0.78 | KDM4E (0.41) | ALDH1A1MAPTNPC1RAB9AHPGD | |
| SCHEMBL10667400 | 0.76 | KDM4E (0.40) | ALDH1A1MAPTNPC1RAB9AHPGD | |
| SCHEMBL10667408 | 0.76 | KDM4E (0.40) | ALDH1A1MAPTNPC1RAB9AHPGD | |
| SCHEMBL10665789 | 0.75 | CDC25A (0.42) | ALDH1A1MAPTNPC1RAB9AHPGD | |
| SCHEMBL10664577 | 0.74 | CDC25A (0.44) | ALDH1A1MAPTHPGDS1PR1SMN1; SMN2 | |
| SCHEMBL10662819 | 0.74 | CDC25A (0.44) | ALDH1A1MAPTHPGDS1PR1SMN1; SMN2 | |
| SCHEMBL10661502 | 0.74 | CDC25A (0.44) | ALDH1A1MAPTHPGDS1PR1SMN1; SMN2 | |
| SCHEMBL10661496 | 0.74 | CDC25A (0.44) | ALDH1A1MAPTHPGDS1PR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | disclosed |