Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 7/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | STAT6 | P42226 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617196 | 0.89 | APLNR (0.42) | UGT2B7APLNRFFAR3CYP2C19NFKB1 | |
| SCHEMBL14825423 | 0.79 | UGT2B7 (0.35) | UGT2B7FFAR3CYP2C19NFKB1TSHR | |
| SCHEMBL11057536 | 0.75 | FFAR3 (0.40) | APLNRFFAR3 | |
| SCHEMBL8989857 | 0.75 | UGT2B7 (0.33) | UGT2B7CYP3A4MAPTRECQLSMN1; SMN2 | |
| SCHEMBL31697963 | 0.72 | UGT2B7 (0.31) | UGT2B7 | |
| SCHEMBL14196109 | 0.71 | ALDH1A1 (0.43) | UGT2B7CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL23364672 | 0.70 | SLC1A2 (0.42) | UGT2B7APLNRFFAR3CYP2C19NFKB1 | |
| SCHEMBL31455072 | 0.70 | APLNR (0.36) | APLNRTSHRMAPT | |
| SCHEMBL11246132 | 0.70 | APLNR (0.36) | UGT2B7APLNRFFAR3SLC1A2SLC1A1 | |
| SCHEMBL22219393 | 0.69 | ALDH1A1 (0.39) | UGT2B7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272279-A1 | PROCESS FOR PRODUCING DIAMINOALKANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |
| WO-1987007312-A1 | PROCESS FOR PRODUCING DIAMINOALKANE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (JP) | 1987-12-03 | — | — | WO | disclosed |