Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671926 | 0.85 | MEN1 (0.42) | LMNAMEN1KMT2AGAACYP1A2 | |
| SCHEMBL10668306 | 0.83 | RAB9A (0.56) | LMNAMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL10668969 | 0.81 | ALDH1A1 (0.55) | LMNAMEN1KMT2AGAACYP1A2 | |
| SCHEMBL7143965 | 0.77 | KDM4E (0.64) | MEN1KMT2AGAACYP1A2CYP2C9 | |
| SCHEMBL16908932 | 0.76 | GAA (0.60) | LMNAMEN1KMT2AGAACYP1A2 | |
| SCHEMBL10668038 | 0.71 | CDC7 (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10668031 | 0.71 | CDC7 (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL10664404 | 0.70 | CDC7 (0.56) | LMNAMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL3314292 | 0.70 | ALDH1A1 (0.55) | LMNAMEN1KMT2AGAACYP1A2 | |
| Hydrochloric Acid SCHEMBL7138896 | 0.70 | KDM4E (0.50) | MEN1KMT2AGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4735957-A | ANTIULCER AGENTS, CARDIOTONIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| US-4649146-A | ANTIULCER | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0117082-A2 | Thiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-29 | — | — | EP | disclosed |