Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | CCR1 | P32246 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10672727 | 0.90 | ALDH1A1 (0.57) | MAPTLMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL10670972 | 0.87 | MAPT (0.53) | CNR1CCR1SIGMAR1MAPTLMNA | |
| SCHEMBL15556551 | 0.80 | CNR1 (0.63) | CNR1CCR1SIGMAR1MAPTLMNA | |
| SCHEMBL5534769 | 0.77 | CNR1 (0.59) | CNR1CCR1SIGMAR1MAPTLMNA | |
| SCHEMBL10671588 | 0.72 | ALDH1A1 (0.62) | CCR1MAPTLMNAHTTALDH1A1 | |
| SCHEMBL1193355 | 0.72 | ALDH1A1 (0.63) | CNR1MAPTLMNAHTTALDH1A1 | |
| SCHEMBL28811687 | 0.72 | ALDH1A1 (0.63) | CNR1MAPTLMNAHTTNAMPT | |
| SCHEMBL11087646 | 0.72 | CNR1 (0.51) | CNR1CCR1SIGMAR1MAPTLMNA | |
| SCHEMBL2241959 | 0.72 | ALDH1A1 (0.67) | CNR1SIGMAR1MAPTLMNAHTT | |
| SCHEMBL25167083 | 0.72 | CNR1 (0.53) | CNR1CCR1SIGMAR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782071-A | Tetrasubstituted urea cholinergic agents | WARNER-LAMBERT COMPANY (US) | 1988-11-01 | — | — | US | disclosed |