Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668646 | 0.87 | CNR1 (0.59) | MAPTNPSR1LMNAHTTSIGMAR1 | |
| SCHEMBL10672727 | 0.77 | ALDH1A1 (0.57) | MAPTLMNAHTTNPC1ALDH1A1 | |
| SCHEMBL5542441 | 0.77 | ALDH1A1 (0.60) | MAPTNPSR1LMNAHTTSIGMAR1 | |
| SCHEMBL5534769 | 0.75 | CNR1 (0.59) | MAPTNPSR1LMNAHTTSIGMAR1 | |
| SCHEMBL15556551 | 0.75 | CNR1 (0.63) | MAPTNPSR1LMNAHTTSIGMAR1 | |
| SCHEMBL4602817 | 0.75 | ALDH1A1 (0.66) | MAPTNPSR1LMNAHTTSIGMAR1 | |
| SCHEMBL14393509 | 0.74 | QDPR (0.67) | MAPTNPSR1LMNAHTTSIGMAR1 | |
| SCHEMBL14197130 | 0.73 | NAMPT (0.58) | MAPTLMNASIGMAR1NPC1ALDH1A1 | |
| SCHEMBL8093113 | 0.73 | DRD2 (0.53) | MAPTNPSR1LMNAHTTSIGMAR1 | |
| SCHEMBL14224507 | 0.70 | MAPK1 (0.58) | MAPTSIGMAR1NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782071-A | Tetrasubstituted urea cholinergic agents | WARNER-LAMBERT COMPANY (US) | 1988-11-01 | — | — | US | disclosed |