Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668062 | 0.94 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL9872868 | 0.87 | RAB9A (0.58) | RAB9AMAPTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL15031615 | 0.84 | RAB9A (0.68) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL9871275 | 0.83 | RAB9A (0.53) | RAB9AMAPTSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL9872136 | 0.82 | RAB9A (0.60) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL9871916 | 0.81 | RAB9A (0.59) | RAB9AMAPTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL8298007 | 0.80 | RAB9A (0.79) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL2330814 | 0.80 | RAB9A (0.61) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL30839868 | 0.79 | TERT (0.74) | MAPTNPC1NR1I2POLBAHR | |
| SCHEMBL1569149 | 0.79 | TERT (0.74) | MAPTNPC1NR1I2POLBAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764612-A | SELECTIVE HISTAMINE H2-ANTAGONIST | GLAXO GROUP LIMITED (GB) | 1988-08-16 | — | — | US | disclosed |
| US-4442110-A | ANTISECRETORY, ANTIALLERGEN, ANTIINFLAMMATORY, ANTIULCER | GLAXO GROUP LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |
| US-4318913-A | 1,2,4-Triazole-3,5-diamine derivatives | GLAXO GROUP LIMITED (GB) | 1982-03-09 | — | — | US | disclosed |