Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 9/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830993 | 0.96 | TSHR (0.39) | TSHRCCR4 | |
| SCHEMBL10667964 | 0.92 | TSHR (0.39) | TSHRCCR4 | |
| SCHEMBL10659376 | 0.91 | TSHR (0.36) | TSHRCCR4 | |
| SCHEMBL10660632 | 0.91 | CCR4 (0.39) | TSHRCCR4 | |
| SCHEMBL10662537 | 0.91 | CCR4 (0.39) | TSHRCCR4 | |
| SCHEMBL10665608 | 0.88 | ACLY (0.39) | TSHRCCR4 | |
| SCHEMBL10660918 | 0.88 | LCK (0.37) | TSHRCCR4 | |
| SCHEMBL10663456 | 0.87 | TSHR (0.38) | TSHRCCR4FFAR4 | |
| SCHEMBL10665531 | 0.87 | TSHR (0.38) | TSHRCCR4FFAR4 | |
| SCHEMBL10658673 | 0.87 | SMN1; SMN2 (0.34) | TSHRCCR4FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755212-A | Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn | THE DOW CHEMICAL COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4741764-A | SUPPRESSION OF NITRIFICATION OF AMMONIUM NITROGEN IN THE SOIL | THE DOW CHEMICAL COMPANY (US) | 1988-05-03 | — | — | US | disclosed |
| US-4740233-A | Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |