Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 7/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10666757 | 0.91 | CCR4 (0.36) | SMN1; SMN2HIF1ACCR4TSHR | |
| SCHEMBL9830993 | 0.89 | TSHR (0.39) | CCR4TSHR | |
| SCHEMBL10661779 | 0.88 | PTGS2 (0.35) | CCR4TSHR | |
| SCHEMBL10668804 | 0.87 | TSHR (0.38) | CCR4TSHRFFAR4 | |
| SCHEMBL10667964 | 0.85 | TSHR (0.39) | CCR4TSHR | |
| SCHEMBL10666342 | 0.85 | METTL3 (0.38) | SMN1; SMN2 | |
| SCHEMBL10662537 | 0.84 | CCR4 (0.39) | CCR4TSHR | |
| SCHEMBL10659376 | 0.84 | TSHR (0.36) | CCR4TSHR | |
| SCHEMBL10660632 | 0.84 | CCR4 (0.39) | CCR4TSHR | |
| SCHEMBL10667649 | 0.84 | MAPT (0.34) | SMN1; SMN2CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755212-A | Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn | THE DOW CHEMICAL COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4741764-A | SUPPRESSION OF NITRIFICATION OF AMMONIUM NITROGEN IN THE SOIL | THE DOW CHEMICAL COMPANY (US) | 1988-05-03 | — | — | US | disclosed |
| US-4740233-A | Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |