Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678590 | 1.00 | FFAR1 (0.41) | FFAR1FFAR4MMP2MMP12GPR84 | |
| SCHEMBL10671140 | 0.81 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12GPR84 | |
| SCHEMBL10671133 | 0.81 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12GPR84 | |
| SCHEMBL5209866 | 0.78 | KCNH2 (0.41) | FFAR1FFAR4MMP2MMP12GPR84 | |
| SCHEMBL6310346 | 0.76 | GRM5 (0.40) | FFAR1FFAR4 | |
| Methane SCHEMBL7680666 | 0.76 | GPR84 (0.43) | FFAR1FFAR4MMP2MMP12GPR84 | |
| SCHEMBL7680659 | 0.75 | KCNH2 (0.42) | FFAR1FFAR4MMP2MMP12GPR84 | |
| SCHEMBL3740319 | 0.74 | GRM5 (0.36) | MMP2MMP12 | |
| SCHEMBL7685513 | 0.73 | GPR84 (0.39) | FFAR1FFAR4MMP2MMP12GPR84 | |
| SCHEMBL7686725 | 0.73 | CYP2A6 (0.47) | FFAR1FFAR4MMP2MMP12GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732901-A | BRONCHODILATORS | BEECHAM GROUP P.L.C. (GB) | 1988-03-22 | — | — | US | disclosed |
| EP-0194093-A2 | Substituted heterocyclic acrylic acids and esters, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1986-09-10 | — | — | EP | disclosed |