Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL7680666 | 0.81 | GPR84 (0.43) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL7680659 | 0.80 | KCNH2 (0.42) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL7678590 | 0.78 | FFAR1 (0.41) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL10669115 | 0.78 | FFAR1 (0.41) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL29084193 | 0.75 | KCNH2 (0.46) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL2493079 | 0.74 | FFAR1 (0.40) | FFAR1FFAR4MMP2MMP12GPR84 | |
| SCHEMBL5886652 | 0.74 | FFAR1 (0.63) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL7683336 | 0.72 | FFAR1 (0.39) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL5886550 | 0.72 | KCNH2 (0.59) | KCNH2FFAR1FFAR4MMP2MMP12 | |
| SCHEMBL2582382 | 0.71 | KCNH2 (0.46) | KCNH2FFAR1FFAR4MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980867-B1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-6100292-A | Ketone derivatives and their medical applications | TORAY INDUSTRIES, INC. (JP) | 2000-08-08 | — | — | US | disclosed |
| EP-0980867-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-02-23 | — | — | EP | disclosed |