SCHEMBL1066946

SCHEMBL1066946

CCCCCCCCCCCCCCCCCCOc1c(CCCC)cc(CCC(=O)O)cc1CCCC

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRA P10827 6/20 0.71
THRB P10828 6/20 0.71
LTB4R Q15722 2/20 0.46
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LTB4R2 Q9NPC1 1/20 0.45
PLA2G4B P0C869 1/20 0.44
S1PR4 O95977 1/20 0.43
S1PR1 P21453 1/20 0.43
S1PR3 Q99500 1/20 0.43
PLA2G2A P14555 1/20 0.43
FFAR1 O14842 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
GPR17 Q13304 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20527124 0.84 THRA (0.72) THRATHRBLTB4RLMNAL3MBTL1
SCHEMBL4895878 0.83 THRB (1.00) THRATHRBS1PR1S1PR3
SCHEMBL4898278 0.81 THRB (0.97) THRATHRBS1PR1S1PR3
SCHEMBL19174669 0.80 THRA (0.54) THRATHRBPLA2G4B
SCHEMBL15005367 0.79 THRA (0.54) THRATHRBFFAR1FFAR4
SCHEMBL4854721 0.79 THRA (0.49) THRATHRBLMNAL3MBTL1FFAR1
SCHEMBL19193897 0.78 THRA (0.63) THRATHRBLTB4RLMNAL3MBTL1
SCHEMBL11822469 0.77 THRA (0.51) THRATHRBFFAR1FFAR4
SCHEMBL14992318 0.76 THRA (0.45) THRATHRBLMNA
SCHEMBL14975106 0.76 THRA (0.45) THRATHRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1741752-B1 MOLDED AROMATIC POLYCARBONATE AND RESIN COMPOSITION ASAHI KASEI CHEMICALS CORP (JP) 2011-01-05 EP disclosed
EP-1741752-A1 MOLDED AROMATIC POLYCARBONATE AND RESIN COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2007-01-10 EP disclosed