Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21525583 | 0.78 | CTSA (0.50) | CTSA | |
| SCHEMBL2039261 | 0.75 | CTSA (0.48) | CTSA | |
| SCHEMBL2040743 | 0.75 | CTSA (0.40) | CTSA | |
| SCHEMBL10585713 | 0.75 | CTSA (0.50) | CTSA | |
| SCHEMBL21552487 | 0.74 | CTSA (0.47) | CTSA | |
| SCHEMBL4558251 | 0.74 | CTSA (0.39) | CTSA | |
| SCHEMBL2041450 | 0.73 | CTSA (0.46) | CTSA | |
| SCHEMBL7822031 | 0.72 | CTSA (0.48) | CTSA | |
| SCHEMBL21552119 | 0.72 | CTSA (0.45) | CTSA | |
| SCHEMBL7825710 | 0.71 | CTSA (0.47) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772717-A | Novel process for the preparation of biotin | PFIZER INC. (US) | 1988-09-20 | — | — | US | disclosed |
| US-4732988-A | Bicyclic precursors for the preparation of biotin | PFIZER INC. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4694087-A | Imidazolidinone precursors for the preparation of biotin | PFIZER INC. (US) | 1987-09-15 | — | — | US | disclosed |
| US-4631345-A | Thiazole precursors for the preparation of biotin | PFIZER INC. (US) | 1986-12-23 | — | — | US | disclosed |
| US-4581459-A | Process for the preparation of biotin | PFIZER INC. (US) | 1986-04-08 | — | — | US | disclosed |
| US-4468516-A | Process for the preparation of biotin | PFIZER INC. (US) | 1984-08-28 | — | — | US | disclosed |
| EP-0094776-A2 | Novel process for the preparation of biotin | PFIZER INC. (US) | 1983-11-23 | — | — | EP | disclosed |