SCHEMBL4558251

SCHEMBL4558251

CC(N)(C(=O)O)C(CS)c1nccs1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSA P10619 15/20 0.39
ALDH1A1 P00352 1/20 0.34
NR3C1 P04150 1/20 0.34
ALOX12 P18054 2/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10669573 0.74 CTSA (0.49) CTSA
SCHEMBL2040743 0.68 CTSA (0.40) CTSAALDH1A1NR3C1
SCHEMBL21552311 0.67 NR3C1 (0.41) CTSAALDH1A1NR3C1
SCHEMBL21552407 0.67 NR3C1 (0.39) CTSANR3C1
Oxalic Acid SCHEMBL7013062 0.66 ALDH1A1 (0.41) CTSAALDH1A1
SCHEMBL5585939 0.66 ALDH1A1 (0.43) CTSAALDH1A1
SCHEMBL11083464 0.65 GRIK1 (0.40) CTSAALDH1A1
SCHEMBL909602 0.65 ALDH1A1 (0.44) CTSAALDH1A1
SCHEMBL1582982 0.65 GRIK1 (0.40) CTSAALDH1A1
SCHEMBL2398682 0.65 CTSA (0.40) CTSAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009151744-A1 S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES GALLEON PHARMACEUTICALS, INC. (US) 2009-12-17 WO disclosed