Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Irloxacin SCHEMBL145215 | 0.91 | DRD3 (0.67) | ALDH1A1DRD3KDM4EHSD17B10HPGD | |
| SCHEMBL10372171 | 0.91 | ALDH1A1 (0.67) | ALDH1A1DRD3CNR1CNR2KDM4E | |
| Irloxacin SCHEMBL9743690 | 0.90 | DRD3 (0.66) | ALDH1A1DRD3KDM4EHSD17B10HPGD | |
| SCHEMBL10369898 | 0.90 | ALDH1A1 (0.57) | ALDH1A1DRD3CNR1CNR2KDM4E | |
| Irloxacin SCHEMBL9743701 | 0.90 | DRD3 (0.66) | ALDH1A1DRD3KDM4EHSD17B10HPGD | |
| SCHEMBL10673419 | 0.87 | ALDH1A1 (0.58) | ALDH1A1DRD3CNR1CNR2KDM4E | |
| SCHEMBL15282020 | 0.85 | ALDH1A1 (0.59) | ALDH1A1DRD3KDM4EHSD17B10HPGD | |
| SCHEMBL10672669 | 0.84 | ALDH1A1 (0.50) | ALDH1A1DRD3CNR1CNR2KDM4E | |
| SCHEMBL10668065 | 0.83 | ALDH1A1 (0.53) | ALDH1A1DRD3CNR1CNR2KDM4E | |
| SCHEMBL15282135 | 0.82 | ALDH1A1 (0.86) | ALDH1A1DRD3KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727080-A | BACTERICIDES, FUNGICIDES | PROVESAN S.A. (CH) | 1988-02-23 | — | — | US | claimed |
| US-4727080-A | BACTERICIDES, FUNGICIDES | PROVESAN S.A. (CH) | 1988-02-23 | — | — | US | disclosed |