Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | PPOX | P50336 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14896568 | 0.85 | TDP1 (0.67) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10552727 | 0.82 | TDP1 (0.76) | TDP1MEN1TTRPPOXKMT2A | |
| Hydrochloric Acid SCHEMBL10553440 | 0.81 | MEN1 (0.74) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10658377 | 0.81 | TDP1 (0.57) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL9751309 | 0.80 | TDP1 (0.70) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10961789 | 0.80 | TDP1 (0.72) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL31118239 | 0.80 | MEN1 (0.55) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL28544623 | 0.79 | TDP1 (0.62) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10668736 | 0.78 | TDP1 (0.64) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL8601303 | 0.78 | TDP1 (0.83) | TDP1MEN1TTRPPOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778914-A | FOR HALOGENATED DIPHENYL ETHER HERBICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-18 | — | — | US | disclosed |